Antibody Drug Discovery by Clive R. Wood (2011, Hardcover)

Description: Monoclonal antibodies have become important treatments for cancer, inflammation and a wide range of other diseases, representing an increasing share of the most successful pharmaceutical markets. The technologies to discover these drugs have been developed by select centers of excellence in industry and academia, and are continually being fine tuned in the race to identify the best antibody-based drug candidates and accelerate their paths to patients. The objective of this volume is to provide a series of guides to those evaluating and preparing to enter particular areas within the field and to offer specialized perspectives to established researchers. The chapters set into context the significance of key developments and important considerations for selecting different approaches, such as antibody humanization, isotype selection, lead candidate selection criteria and protein production. All contributors to this work are experts in their fields, and many have played pivotal roles in the creation of these technologies. Editorial ReviewsFrom the Back CoverAntibody-based therapeutics are a central driver of the success of biopharmaceuticals. The discovery technology of this field is isolated to a limited number of centers of excellence in industry and academia. The objective of this volume is to provide a series of guides to those evaluating and preparing to enter particular areas within the field. Each chapter is written with a historical perspective that sets into context the significance of the key developments, and with the provision of "points to consider" for the reader as a value-added feature of the volume. All contributors are experts in their fields and have played pivotal roles in the creation of the technology. --This text refers to the hardcover edition.From the Inside FlapAntibody-based therapeutics are a central driver of the success of biopharmaceuticals. The discovery technology of this field is isolated to a limited number of centers of excellence in industry and academia. The objective of this volume is to provide a series of guides to those evaluating and preparing to enter particular areas within the field. Each chapter is written with a historical perspective that sets into context the significance of the key developments, and with the provision of "points to consider" for the reader as a value-added feature of the volume. All contributors are experts in their fields and have played pivotal roles in the creation of the technology.Product detailsASIN ‏ : ‎ B00741CJI4Publisher ‏ : ‎ Imperial College Press; Illustrated edition (December 2, 2011)Publication date ‏ : ‎ December 2, 2011Language ‏ : ‎ EnglishFile size ‏ : ‎ 6133 KBText-to-Speech ‏ : ‎ EnabledScreen Reader ‏ : ‎ SupportedEnhanced typesetting ‏ : ‎ EnabledX-Ray ‏ : ‎ Not EnabledWord Wise ‏ : ‎ Not EnabledSticky notes ‏ : ‎ On Kindle ScribePrint length ‏ : ‎ 450 pages

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