Description: Recombinant Human IL-10Product SpecificationsExpression of Human Proteins in Human CellsExtreme low EndotoxinHigh PurityAnimal Free and Xeno FreeTag FreeSource: Human cells derivedStructure: Glycosylated monomerPurity: >95% by SDS-PAGEEndotoxin Level: <0.5EU/ugMolecular Weight: 17kDaFormulation: Lyophilized from a 0.2μm filtered solution in PBS without carrier proteinActivity AssayThe activity was measured by its ability to stimulate the proliferation of MC/9-2 cells (mouse master cell line).ReconstitutionBriefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.Stability & StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to -80°C under sterile conditions after reconstitution.Protein DescriptionInterleukin 10 (IL-10) is a member of the IL-10 family of α-helical cytokines. IL-10 is an immunosuppressive cytokine produced by a variety of mammalian cell types including macrophages, monocytes, T cells, B cells and keratinocytes. IL-10 inhibits the expression of a number of proinflammatory cytokines such as IFN- gamma, IL-2, IL-3, TNF and GM-CSF. Like IL-4, IL-10 enhances humoral immune responses and attenuates cell-mediated immune reactions.ReferencesGesser B, et al. (1997) Proc. Natl. Acad. Sci. U.S.A. 94,14620-14625.Sabat R, et al. (2010) Cytokine Growth Factor Rev. 21,331.
Price: 49.99 USD
Location: Livermore, California
End Time: 2025-01-08T21:08:33.000Z
Shipping Cost: 11 USD
Product Images
Item Specifics
All returns accepted: ReturnsNotAccepted
Brand: StemImmune LLC
Unit Type: Unit
Volume/Quantity: 10ug/vial
Custom Bundle: No
MPN: HCT-I10-0010
Country/Region of Manufacture: United States
Unit Quantity: 10ug/vial
Intended Use/Discipline: Anesthesiology, Biological Laboratory, Cardiology, Cosmetology, Dental Laboratory, Dentistry, Dermatology, Emergency Medicine, Endocrinology, Endodontics
