Description: Understanding Insulin Action by J. Espinal Every year between three and four hundred papers are published on the topic of insulin action. I intend to present a review of the physiological effects of insulin, the pathology of defects in the action of insulin, and the current views on the mechanism of action of this hormone. FORMAT Paperback LANGUAGE English CONDITION Brand New Publisher Description Every year between three and four hundred papers are published on the topic of insulin action. This extraordinary publication rate prevents any author from includ ing an exhaustive bibliography in any review or book. Perhaps due to this there is no single text that attempts to cover the effects and the mechanism of action of insulin. This book is such an attempt. I intend to present a review of the physiological effects of insulin, the pathology of defects in the action of insulin, and the current views on the mechanism of action of this hormone. I make no apology for the fact that the bibliography will not be extensive and that the amount of experimental detail and data discussed will be kept to a relevant minimum. This book is not intended for the expert in the field, but for the second- or third-year undergraduate and graduate student of medicine, biochemistry, physiology or related disciplines, and will be valuable as a reference source for research workers. The book is presented as a guide, a summary of the ideas and facts; it will present a reader with a foretaste of a fascinating and ever-changing field. I have attempted to be up-to-date with published research work. Any significant contributions to the field not included in the first draft have been added as footnotes. I assume a basic knowledge of the metabolic pathways of carbohydrates, fats and proteins. Table of Contents 1 Introduction.- 1.1 A short account of the discovery of insulin.- 1.2 An overview of insulin action and diabetes.- 2 Insulin: Chemistry, Synthesis and Secretion.- 2.1 The insulin molecule.- 2.2 Insulin synthesis.- 2.3 Insulin secretion.- 3 Pathophysiology of Insulin.- 3.1 Introduction.- 3.3 Diabetes.- 4 Molecular Mechanisms Involved in Insulin Action.- 4.1 Regulation of protein phosphorylation.- 4.2 Insulin regulation of protein traffic.- 4.3 Regulation of gene expression.- 5 The Insulin Receptor.- 5.1 Receptor structure.- 5.2 The insulin receptor tyrosine kinase.- 5.3 Insulin receptor internalization.- 6 Molecular Mechanisms of Insulin Signal Transduction.- 6.1 The cAMP system.- 6.2 The inositoltrisphosphate-diacylglycerol system.- 6.3 The involvement of glycosylphosphatidylinositol (GPI) in insulin action.- 7 Summary and Perspectives.- 7.1 Summary.- 7.2 Perspectives. Promotional Springer Book Archives Long Description Every year between three and four hundred papers are published on the topic of insulin action. This extraordinary publication rate prevents any author from includ Details ISBN1461287944 Author J. Espinal Pages 129 Language English ISBN-10 1461287944 ISBN-13 9781461287940 Media Book Format Paperback DEWEY 571.2 Series Number 16 Imprint Springer-Verlag New York Inc. Subtitle Principles and Molecular Mechanisms Country of Publication United States Year 2011 Publication Date 2011-11-11 Place of Publication New York, NY Short Title UNDERSTANDING INSULIN ACTION 1 UK Release Date 2011-11-11 AU Release Date 2011-11-11 NZ Release Date 2011-11-11 US Release Date 2011-11-11 Illustrations 129 p. Publisher Springer-Verlag New York Inc. Edition Description Softcover reprint of the original 1st ed. 1989 Series Ettore Majorana International Science Series Alternative 9780412022616 Audience Professional & Vocational We've got this At The Nile, if you're looking for it, we've got it. With fast shipping, low prices, friendly service and well over a million items - you're bound to find what you want, at a price you'll love! TheNile_Item_ID:137764959;
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ISBN-13: 9781461287940
Book Title: Understanding Insulin Action
Number of Pages: 129 Pages
Language: English
Publication Name: Understanding Insulin Action: Principles and Molecular Mechanisms
Publisher: Springer-Verlag New York Inc.
Publication Year: 2011
Subject: Chemistry, Biology
Item Height: 235 mm
Item Weight: 219 g
Type: Textbook
Author: J. Espinal
Item Width: 155 mm
Format: Paperback
